Buspirone comes as a tablet to take by mouth. It usually is taken two or three times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take buspirone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

BUSPIRONE DRUG INFO

Buspirone is used to treat anxiety disorders or in the short-term treatment of symptoms of anxiety.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How should this medicine be used?

Buspirone comes as a tablet to take by mouth. It usually is taken two or three times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take buspirone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Continue to take buspirone even if you feel well. Do not stop taking buspirone without talking to your doctor, especially if you have taken large doses for a long time. Your doctor probably will decrease your dose gradually. This drug must be taken regularly for a few weeks before its full effect is felt.

Other uses for this medicine

Buspirone is used to treat the symptoms of premenstrual syndrome. Talk to your doctor about the possible risks of using this drug for your condition.

What special precautions should I follow?

Before taking buspirone,

• tell your doctor and pharmacist if you are allergic to buspirone or any other drugs.
• tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially antihistamines; anticonvulsants such as carbamazepine (Tegretol), phenobarbital (Barbita, Luminal, Solfoton), and phenytoin (Dilantin); dexamethasone (Decadron, others); diazepam (Valium); diltiazem (Cardizem, Dilacor, Tiazac); erythromycin ((E.E.S., E-Mycin, Erythrocin, others); haloperidol (Haldol); ketoconazole (Nizoral); itraconazole (Sporanox); MAO inhibitors [phenelzine (Nardil) and tranylcypromine (Parnate)]; muscle relaxants; nefazodone (Serzone); pain medications or narcotics; rifampin (Rifadin, Rimactane); ritonavir (Norvir); sedatives; sleeping pills; tranquilizers; trazodone (Desyrel); verapamil (Calan, Covera, Verelan); and vitamins.
• tell your doctor if you have or have ever had kidney or liver disease or a history of alcohol or drug abuse.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking buspirone, call your doctor.
• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking buspirone.
• you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.
• remember that alcohol can add to the drowsiness caused by this drug.

What special dietary instructions should I follow?

You may take buspirone either with or without food, but take it consistently, either always with food or always without food.

Avoid drinking large amounts of grapefruit juice while taking buspirone.

What should I do if I forget a dose?

Take the missed dose as soon as you remember it. However, if it is within 4 hours of the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?

Although side effects from buspirone are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:

• drowsiness
• upset stomach
• vomiting
• constipation
• diarrhea
• stomach pain
• headache
• dry mouth
• depression
• excitement
• fatigue
• nervousness
• difficulty sleeping
• lightheadedness
• weakness
• numbness

If you experience any of the following symptoms, call your doctor immediately:

• skin rash
• itching
• fast or irregular heartbeat
• blurred vision
• unusual movements or the head or neck muscles

What storage conditions are needed for this medicine?

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature, away from light, excess heat, and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

• upset stomach
• vomiting
• dizziness
• drowsiness
• blurred vision

What other information should I know?

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to buspirone.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

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Buspirone (byoo-SPYE-rone) is used to treat certain anxiety disorders or to relieve the symptoms of anxiety. However, buspirone usually is not used for anxiety or tension caused by the stress of everyday life. It is not known exactly how buspirone works to relieve the symptoms of anxiety. Buspirone is thought to work by decreasing the amount and actions of a chemical known as serotonin in certain parts of the brain.

BUSPAR DRUG INFO

BUSPIRONE – ORAL (byou-SPY-rown)

COMMON BRAND NAME(S): Buspar

USES: Buspirone is used to relieve nervousness, anxiety and tension.

OTHER USES: This medication may also be used for premenstrual syndrome.

HOW TO USE: Take this medication with food or milk if stomach upset occurs. It is important to take this medication exactly as prescribed. Do not increase your dose or take more often than prescribed. Symptoms will begin to improve within 7 to 10 days of starting this medication. However, it may take 3 to 4 weeks for the full benefit of the medication to be apparent.

SIDE EFFECTS: This medication may cause drowsiness, dizziness, lightheadedness, fatigue, weakness, vivid dreams, sleeplessness, dry skin, blurred vision, altered sense of taste and smell, weight gain, muscle aches, ringing in the ears, nausea, headaches. If these effects persist or worsen, notify your doctor. Notify your doctor if you experience: abnormal movements or “twitches” of the face or neck muscles, other involuntary movements or tremors, depression, confusion, incoordination, chest pain, breathing difficulties. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: Before taking buspirone, tell your doctor your medical history especially: kidney or liver disease, any drug allergies. Limit alcohol intake as it may intensify the dizziness and/or drowsiness effects of buspirone. Use caution when engaging in activities requiring alertness such as driving. Tell your doctor if you are pregnant before using this drug. It is not known if this drug is excreted into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Before taking buspirone tell your doctor of all over-the-counter or prescription drugs you may use especially: other drugs for anxiety or depression, MAOIs (e.g., phenelzine, tranylcypromine, isocarboxazid, selegiline, linezolid, furazolidone), azole or macrolide antibiotics, haloperidol, narcotic pain medications. Do not eat grapefruit or drink grapefruit juice unless your doctor instructs you otherwise. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include nausea, vomiting, dizziness, drowsiness, and decreased pupil size.

NOTES: Do not share this medication with others.

MISSED DOSE: Take any missed dose as soon as possible but not if it is almost time for the next dose. If it is time for the next dose, skip the missed dose and resume your regular schedule. Do not “double-up” the dose. If more than one dose is missed, contact your doctor or pharmacist to establish a new dosing schedule.

STORAGE: Store at room temperature and keep away from moisture and sunlight. Do not store in the bathroom.

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